Calcium strengthens bones, and it also facilitates the body’s every muscle contraction and hormone secretion. View abstract. View abstract. Br.J Nutr 2004;91(4):625-634. Am J Geriatr Pharmacother. J Reprod Med 1999;44:601-5. New Engl J Med 1984;310:1221-5. Calcium can attach to some antibiotics called tetracyclines in the stomach. Am J Clin Nutr 1998;67(6):1273-1278. Med.Sci.Sports Exerc. Joint Bone Spine 2009;76(6):637-641. Nephron Clin Pract. Salazar-Martinez, E., Lazcano-Ponce, E., Sanchez-Zamorano, L. M., Gonzalez-Lira, G., Escudero-DE Los, Rios P., and Hernandez-Avila, M. Dietary factors and endometrial cancer risk. View abstract. 2009;16(3):e407-e429. J Hypertens 1998;16:1693-9. If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Freudenheim, J. L., Johnson, N. E., and Smith, E. L. Relationships between usual nutrient intake and bone-mineral content of women 35-65 years of age: longitudinal and cross-sectional analysis. View abstract. 1987;294(4):219-224. Cochrane.Database.Syst.Rev. Endocrinol Jpn. Am J Clin Nutr 2000;71:1530-5. Spinal bone loss in postmenopausal women supplemented with calcium and trace minerals. Waal-Manning HJ, McNab M, Paulin JM, and et al. View abstract. Psychopharmacol Bull 1991;27:145-8. Hsia J, Heiss G, Ren H, et al. Shigematsu, T. Multicenter prospective randomized, double-blind comparative study between lanthanum carbonate and calcium carbonate as phosphate binders in Japanese hemodialysis patients with hyperphosphatemia. Lanou, A. J., Berkow, S. E., and Barnard, N. D. Calcium, dairy products, and bone health in children and young adults: a reevaluation of the evidence. Woo, J., Sum, C., Yiu, H. H., Ip, K., Chung, L., and Ho, L. Efficacy of a specially designed hip protector for hip fracture prevention and compliance with use in elderly Hong Kong Chinese. Maton PN, Burton ME. van Schoor, N. M., Smit, J. H., Twisk, J. W., Bouter, L. M., and Lips, P. Prevention of hip fractures by external hip protectors: a randomized controlled trial. Risk factors for hip fracture in European women: the MEDOS Study. Lau, E., Donnan, S., Barker, D. J., and Cooper, C. Physical activity and calcium intake in fracture of the proximal femur in Hong Kong. View abstract. Wang TJ, Pencina MJ, Booth SL, et al. Oral calcium effectively reduces parathyroid hormone levels in hemodialysis patients: a randomized double-blind placebo-controlled study. Zemel MB, Shi H, Greer B, et al. View abstract. Orimo, H. [Calcium intake and osteoporosis]. Hip protectors and hip fractures. Ushiroyama T, Okamura S, Ikeda A, et al. Some research suggests that taking calcium supplements daily decreases the risk of prostate cancer. Cauley JA, Chlebowski RT, Wactawski-Wende J, et al. Effects of ergocalciferol added to calcium on the risk of falls in elderly high-risk women. Hypertension 1989;13(3):219-226. View abstract. Getting calcium injections might decrease the effectiveness of these medications for high blood pressure. Br.J Cancer 1996;74(1):145-151. J Nutr Elder. Calcium plus vitamin D supplementation and height loss: findings from the Women's Health Initiative Calcium and Vitamin D clinical trial. J Cyst.Fibros. View abstract. Am J Hypertens 2001;14:206S-12S.. View abstract. Your doctor will tell you what an appropriate dose of calcium citrate with vitamin D is for you. Supplementary calcium in prevention of pre-eclampsia. Song X, Li Z, Ji X, Zhang D. Calcium intake and the risk of ovarian cancer: a meta-analysis. Duplechin, R. Y., Nadkarni, M., and Schwartz, R. P. Hypocalcemic tetany in a toddler with undiagnosed rickets. Kanis JA. Ir.Med.J 2001;94(6):172, 174-172, 176. Effect of calcium supplementation on serum cholesterol and blood pressure. Available at: https://wayback.archive-it.org/7993/20171114023216/https://www.fda.gov/Food/IngredientsPackagingLabeling/LabelingNutrition/ucm072771.htm. Nutr Cancer 1987;10(4):181-196. View abstract. Dwyer, J. H., Li, L., Dwyer, K. M., Curtin, L. R., and Feinleib, M. Dietary calcium, alcohol, and incidence of treated hypertension in the NHANES I epidemiologic follow-up study. Your body's calcium needs range higher as you get older. View abstract. Br.J Nutr 2009;101(2):285-294. There are several calcium preparations listed in the British National Formulary (BNF). If you have any questions, ask your doctor or pharmacist. Lund, B., Badskjaer, J., Lund, B., and Soerensen, O. H. Vitamin D and ischaemic heart disease. Nephrol Dial.Transplant. View abstract. Osteoporos.Int 1992;2(3):122-127. View abstract. The effects of divided dose calcium on bone resorption in early postmenopausal women. Sacks, F. M., Brown, L. 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Bolland MJ, Barber PA, Doughty RN, et al. 2003;37(1):12-15. Meese, R. B., Gonzales, D. G., Casparian, J. M., Ram, C. V., Pak, C. M., and Kaplan, N. M. The inconsistent effects of calcium supplements upon blood pressure in primary hypertension. Evidence for efficacy of drugs affecting bone metabolism in preventing hip fracture. Do not use a household spoon. 5-15-2003;60(10):1029-1032. Pfeifer, M., Begerow, B., Minne, H. W., Nachtigall, D., and Hansen, C. Effects of a short-term vitamin D(3) and calcium supplementation on blood pressure and parathyroid hormone levels in elderly women. Results of a two-year, prospective trial. View abstract. Int J Cancer 12-15-2006;119(12):2938-2942. BMJ. View abstract. View abstract. Larsson, S. C., Bergkvist, L., and Wolk, A. View abstract. 2010;20(1):82-85. Acta Med.Scand. View abstract. 1988;128(3):504-514. J Epidemiol.Community Health 2002;56(6):471-472. Moreira-Pfrimer, L. D., Pedrosa, M. A., Teixeira, L., and Lazaretti-Castro, M. Treatment of vitamin D deficiency increases lower limb muscle strength in institutionalized older people independently of regular physical activity: a randomized double-blind controlled trial. Dietary reference intakes for calcium and vitamin D. Institute of Medicine, November 30, 2010. B., Feskanich, D., and Willett, W. C. Milk intake and risk of hip fracture in men and women: a meta-analysis of prospective cohort studies. View abstract. Gillman, M. W., Rifas-Shiman, S. L., Kleinman, K. P., Rich-Edwards, J. W., and Lipshultz, S. E. Maternal calcium intake and offspring blood pressure. Calcitriol treatment is not effective in postmenopausal osteoporosis. 2012 Mar;66(3):408-10. Adachi, J. D., Bensen, W. G., Bell, M. J., Bianchi, F. A., Cividino, A. Lee, H. P., Gourley, L., Duffy, S. W., Esteve, J., Lee, J., and Day, N. E. Colorectal cancer and diet in an Asian population--a case-control study among Singapore Chinese. View abstract. Moreover, the increment in urinary calcium post-load was higher from calcium citrate than from calcium carbonate at all four dosage levels. View abstract. The importance of meeting calcium needs with foods. Calcium citrate may be only part of a complete program of treatment that also includes dietary changes. Fall prevention. Interventions for preventing bone disease in kidney transplant recipients: a systematic review of randomized controlled trials. Steinbach, G., Morotomi, M., Nomoto, K., Lupton, J., Weinstein, I. JAMA 4-3-1987;257(13):1772-1776. BMJ 2010;340:b5463. Some of these antibiotics that might interact with calcium include ciprofloxacin (Cipro), enoxacin (Penetrex), norfloxacin (Chibroxin, Noroxin), sparfloxacin (Zagam), and trovafloxacin (Trovan). Information from this source is evidence-based and objective, and without commercial influence. A., Schramm, M. M., Barresi, M. L., and Kriska, A. M. Postmenopausal bone density and milk consumption in childhood and adolescence. Increasing amounts of dietary fiber provided by foods normalizes physiologic response of the large bowel without altering calcium balance or fecal steroid excretion. Calcium citrate malate is a well-absorbed form of calcium found in some fortified juices . Effect on clinical symptoms and total serum and ionized serum calcium concentrations. View abstract. View abstract. Kidney Int Suppl 2004;90:S25-32. View abstract. View abstract. Pattern of dietary calcium intake and association with bone mineral density. Dietary supplement interactions with antiretrovirals: a systematic review. Prevention of early postmenopausal bone loss: controlled 2-year study in 315 normal females. If you are using the chewable product, chew it well before swallowing. View abstract. Dagnelie PC, Schuurman AG, Goldbohm RA, Van den Brandt PA. J Am Geriatr Soc 2003;51(3):291-299. Part 8: adult advanced cardiovascular life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. View abstract. Bhattacharyya, A. K., Thera, C., Anderson, J. T., Grande, F., and Keys, A. Dietary calcium and fat. The daily dose is divided up and taken between meals. Overall, most research suggests that taking calcium does not reduce the risk for breast cancer. Ann.Intern.Med. Stemmermann, G. N., Nomura, A., and Chyou, P. H. The influence of dairy and nondairy calcium on subsite large-bowel cancer risk. Menopause 2010;17:683-91. J Clin Endocrinol Metab 2005;90(1):44-51. View abstract. Gallagher, J. C. and Goldgar, D. Treatment of postmenopausal osteoporosis with high doses of synthetic calcitriol. Villar, J., Gulmezoglu, A. M., and de, Onis M. Nutritional and antimicrobial interventions to prevent preterm birth: an overview of randomized controlled trials. It is loaded with a clinical strength plant calcium that contains vitamin K2 which in itself is a vehicle that adequately directs calcium to the bones. 2005;12(1):63-68. View abstract. Bone 2000;27:45S. Cao, J. J. and Nielsen, F. H. Acid diet (high-meat protein) effects on calcium metabolism and bone health. Quiz: What Do You Know About Vitamin B12 Deficiency? Effect of dairy calcium on fecal fat excretion: a randomized crossover trial. View abstract. The human body cannot absorb more than 500 milligrams of calcium at a time. Epidemiology 2003;14:206-12.. View abstract. Luengo, M., Pons, F., Martinez de Osaba, M. J., and Picado, C. Prevention of further bone mass loss by nasal calcitonin in patients on long term glucocorticoid therapy for asthma: a two year follow up study. 2010;(8):CD001059. Br J Nutr. 5-26-2011; View abstract. View abstract. Calcium Polyp Prev Study Group. Vallecillo, G., Diez, A., Carbonell, J., and Gonzalez, Macias J. View abstract. Acad.Emerg.Med 1995;2(4):264-273. Does calcium have a dual effect on arterial pressure? Clemens JD, Feinstein AR. 2016;116(1):158-66. View abstract. Sugar-free. Transplantation 10-27-1998;66(8):1004-1008. Gennari C, Chierichetti SM, Bigazzi S, and et al. Clinical, biochemical and histological results of a double-blind trial with 1,25-dihydroxyvitamin D3, estradiol and placebo in post-menopausal osteoporosis. Dairy products and ovarian cancer: a pooled analysis of 12 cohort studies. 1999;24(12):20-21. If you are using the effervescent tablet, allow the tablet to fully dissolve in a glass of water before drinking it. 2002;23(4):570-578. A prospective randomized study for the treatment of bone loss with vitamin d during kidney transplantation in children and adolescents. Al, Sarakbi W., Salhab, M., and Mokbel, K. Dairy products and breast cancer risk: a review of the literature. Effects of Drugs on Clinical Laboratory Tests 4th ed. Effect of physical activity on bone mineral density assessed by limb dominance across the lifespan. J Am Coll Nutr 2002;21:239-44.. View abstract. Frederick, I. O., Williams, M. A., Dashow, E., Kestin, M., Zhang, C., and Leisenring, W. M. Dietary fiber, potassium, magnesium and calcium in relation to the risk of preeclampsia. Zemel MB, Richards J, Milstead A, Campbell P. Effects of calcium and dairy on body composition and weight loss in African-American adults. Kannus, P., Parkkari, J., Niemi, S., Pasanen, M., Palvanen, M., Jarvinen, M., and Vuori, I. Kidney failure. View abstract. Diabetes Care 2005;28:2926-32. Iwamoto, J., Takeda, T., and Sato, Y. Cifuentes M, Riedt CS, Brolin RE, et al. Christiansen, C., Christensen, M. S., McNair, P., Hagen, C., Stocklund, K. E., and Transbol, I. Cumming, R. G. Calcium intake and bone mass: a quantitative review of the evidence. A prospective study of the effects of 1-year calcium-fortified soy milk supplementation on dietary calcium intake and bone health in Chinese adolescent girls aged 14 to 16. Bernstein CN, Seeger LL, Anton PA, et al. Jantti, P. O., Aho, H. J., Maki-Jokela, P. L., and Heikinheimo, R. J. 2016;31(11):2024-2031. Osteoporos.Int 1997;7(3):219-225. View abstract. View abstract. Whelton PK, Kumanyika SK, Cook NR, et al. Effect of calcium supplementation on fracture risk: a double-blind randomized controlled trial. View abstract. Randomized controlled study of calcitonin and etidronate in the treatment of osteoporosis in renal transplant patients [abstract]. JAMA. Am J Kidney Dis. View abstract. J Bone Miner Res 2002;17:709-15. . Rizzoli, R., Chevalley, T., Slosman, D. O., and Bonjour, J. P. Sodium monofluorophosphate increases vertebral bone mineral density in patients with corticosteroid-induced osteoporosis. View abstract. View abstract. Research about how calcium affects the risk of prostate cancer has shown conflicting results. Osteoporos.Int 2005;16(7):799-804. View abstract. 2000;9(1):31-38. 2007;23(6):1341-1349. Mehanna, H. M., Jain, A., Randeva, H., Watkinson, J., and Shaha, A. Postoperative hypocalcemia--the difference a definition makes. MacLean, C., Newberry, S., Maglione, M., McMahon, M., Ranganath, V., Suttorp, M., Mojica, W., Timmer, M., Alexander, A., McNamara, M., Desai, S. B., Zhou, A., Chen, S., Carter, J., Tringale, C., Valentine, D., Johnsen, B., and Grossman, J. Zhang, Q., Hu, X. Q., Ma, G. S., Du, X. Q., Zhu, K., Zhang, X., Tong, R., and Ge, K. Y. View abstract. Calcium can affect your heart. Miller GD, Jarvis JK, McBean LD. Am J Obstet Gynecol 1993;28:1-10. Nippon Naibunpi Gakkai Zasshi 2-20-1991;67(2):84-95. View abstract. View abstract. Vargas Zapata, C. L., Donangelo, C. M., Woodhouse, L. R., Abrams, S. A., Spencer, E. M., and King, J. C. 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A very serious allergic reaction to this drug is rare. View abstract. View abstract. Sotalol (Betapace) interacts with CALCIUM. View abstract. J Hypertens 1986;4(2):241-250. Bischoff-Ferrari HA, Rees JR, Grau MV, and et al. Nephrol Dial.Transplant. Welten, D. C., Kemper, H. C., Post, G. B., and van Staveren, W. A. View abstract. Effects of calcium and calcitriol on bone mass over three years in men with primary osteoporosis- A prospective cross-over study. A double-blind study. Effect of calcitriol on bone loss after cardiac or lung transplantation. Dairy food, calcium, and risk of cancer in the NIH-AARP Diet and Health Study. Weisberg, P., Scanlon, K. S., Li, R., and Cogswell, M. E. Nutritional rickets among children in the United States: review of cases reported between 1986 and 2003. Gallagher, J. C., Fowler, S. E., Detter, J. R., and Sherman, S. S. Combination treatment with estrogen and calcitriol in the prevention of age-related bone loss. 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Effect of vitamin D replacement on musculoskeletal parameters in school children: a randomized controlled trial. View abstract. 4-24-2006;166(8):869-875. Stroke. Baron JA, Tosteson TD, Wargovich MJ, et al. Levi, F., Pasche, C., La, Vecchia C., Lucchini, F., and Franceschi, S. Food groups and colorectal cancer risk. View abstract. Am J Clin Nutr 1991;53(5):1304-1311. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized, placebo-controlled trial. B., Fredriksson, M., Nilsson, E., and Sjodahl, R. Cereal fiber, calcium, and colorectal cancer. Dawson-Hughes B, Harris SS, Krall EA, Dallal GE. Geriátrika 2011;13(6):24-28. View abstract. Am J Clin Nutr 2003;78(6):1188-1193. View abstract. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Meyer, H. E., Henriksen, C., Falch, J. Bijlsma, J. W. Supplementation of vitamin D plus calcium is effective in corticosteroid-induced osteoporosis management. 2007;60(12):1229-1233. A randomized crossover trial comparing sevelamer with calcium acetate in children with CKD. Scand.J Rheumatol. Circulation 10-5-2004;110(14):1990-1995. Cox, M. L., Khan, S. A., Gau, D. W., Cox, S. A., and Hodkinson, H. M. Determinants of forearm bone density in premenopausal women: a study in one general practice. Digoxin, hypercalcaemia, and cardiac conduction. J Clin Endocrinol Metab 1988;67(4):644-650. Cohen, S., Levy, R. M., Keller, M., Boling, E., Emkey, R. D., Greenwald, M., Zizic, T. M., Wallach, S., Sewell, K. L., Lukert, B. P., Axelrod, D. W., and Chines, A. View abstract. BMC.Musculoskelet.Disord. Baron JA, Beach M, Wallace K, et al. Pharmacokinetic and pharmacodynamic comparison of two calcium supplements in postmenopausal women. Ciblos Study Group. Sodium excretion in relation to calcium and hydroxyproline excretion in a healthy Japanese population. An epidemiologic perspective. JAMA 8-18-1993;270(7):841-844. Calcif Tissue Int 1994;54(6):477-480. View abstract. However, there are some people who may still experience gas, bloating, or mild constipation. View abstract. Dr. Willett recommends going lower on calcium and higher on vitamin D than the guidelines suggest—500 to 700 mg a day of calcium and 800 to 1,000 IU of vitamin D. At that rate, you can probably get all or most of your calcium from food, especially if you have a serving or two of dairy products daily. Kanders, B., Dempster, D. W., and Lindsay, R. Interaction of calcium nutrition and physical activity on bone mass in young women. View abstract. Eur.J Clin Nutr 2004;58(5):718-724. Penland JG, Johnson PE. Mao PJ, Zhang C, Tang L, et al. Arch Intern.Med. Colombia Médica (COLOMBIA MEDICA) 2009;40(2):185-93. Terry P, Baron JA, Bergkvist L, et al. 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J., and Pye, D. J. Dietary calcium intake relates to bone mineral density in premenopausal women. Schaefer, K., Scheer, J., Asmus, G., Umlauf, E., Hagemann, J., and von, Herrath D. The treatment of uraemic hyperphosphataemia with calcium acetate and calcium carbonate: a comparative study. 25-hydroxyvitamin D and risk of myocardial infarction in men. Supplementation with calcium + vitamin D enhances the beneficial effect of weight loss on plasma lipid and lipoprotein concentrations. De, Stefani E., Mendilaharsu, M., Deneo-Pellegrini, H., and Ronco, A. Caffeine intake increases the rate of bone loss in elderly women and interacts with vitamin D receptor genotypes. JAMA 8-18-1999;282(7):664-670. 1993;8(4):341-346. Nowson, C. A., Green, R. M., Hopper, J. L., Sherwin, A. J., Young, D., Kaymakci, B., Guest, C. S., Smid, M., Larkins, R. G., and Wark, J. D. A co-twin study of the effect of calcium supplementation on bone density during adolescence. II. Effect of increasing calcium intake on urinary sodium excretion in normotensive subjects. View abstract. October 2005. To avoid this interaction, take bisphosphonate at least 30 minutes before calcium or later in the day. View abstract. Calcium and vitamin D fortified milk supplementation on bone mineral accretion in pre-pubertal girls in Beijing. Trials of Hypertension Prev (TOHP) Collab Res Group. 2002;34(6):2111-2113. Health Technol.Assess. Pereira, M. A., Jacobs, D. R., Jr., Van, Horn L., Slattery, M. L., Kartashov, A. I., and Ludwig, D. S. Dairy consumption, obesity, and the insulin resistance syndrome in young adults: the CARDIA Study. View abstract. Wilkins, C. H., Sheline, Y. I., Roe, C. M., Birge, S. J., and Morris, J. C. Vitamin D deficiency is associated with low mood and worse cognitive performance in older adults. Pilz S, and intervention study [ abstract ] of purgatives are uncommon when... 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